Goed doel. Boeiend en belangwekkend project. Piet van der Veen

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Normal 1baf39ff0260b73073996cdfeba69caf4e1fbc77 iGEM: securing data with DNA iGEM, International Genetically Engineered Machine, is an international annual competition in which multidisciplinary teams of students are using the latest Synthetic Biology techniques to build a biological machine. The students invent, design and build a bacteria with a useful and/or interesting application. This year there are more than 300 teams from universities around the world who participate in the contest. In Boston they present their results and compete for the world title. Every year a team from the University of Groningen participates to show that the faculty of Mathematics and Natural Sciences is one of the best of the world. You can support the team of this year! From the 27th until the 31st of October the 12th edition of the iGEM competition will take place. The team of the University will use the DNA of bacteria as a storage medium for data and use the encryption method on the bacteria. Bio-encryption is increasingly seen as a future way to safely store and exchange millions of gigabytes of data. "Our data are nowadays dependent on digital storage and this will only increase in the future. The digital storage method is vulnerable for hacking and has limited storage capacity. Our aim is to develop a method for data storage and data transfer that can not be hacked by digital means. A non-hackable security system that uses both computer science aspects and molecular biological knowledge. This combination is new and therefore we believe that our project has great potential to win the competition."- Eike Mahlandt, IGEM chairwoman and student Molecular Genetics Participation in the iGEM competition will cost the team a lot of money, including the costs of the laboratory, the materials to build a prototype and participation in the contest. The Faculty supports the iGEM team, but that will not be sufficient to cover all the costs. Would you support the team by making a donation? Any amount is welcome!It is also possible to contribute by starting your own fundraising page which you can use to get sponsored! Bio-encryption The encryption method of Groningen iGEM team will go through several phases. First of all, the original message in regular text will be translated into binary code according to the ASCII notation. This binary message is then encrypted through the use of a computer algorithm and its result will be a new binary message. This message will be saved into the DNA according to the following logic: since DNA has four main components namely TACG, every component will represent a binary pair (combination of a 0 and a 1). The T will be represented as 01, A as 10, C as 00 and G as 11. The goal is to safely send a key and an encrypted message in two separate spore systems of the bacteria Bacillus subtilis. The message is protected by computational encryption, while the sensitive key can only be accessed from the spores with the right growing conditions. For example light-switchable antibiotics have to be activated by the correct frequency of light. If the recipient fails, the sequence will be destroyed and the message lost forever. On the Facebook page of the iGEM team you can find more information on the developments leading up to the competition. € 15.785 Raised € 18.000 Target 87% Reached
Normal 8c465aee0f26200f02bb1af90886c5e768ba5c40 The Dead Sea Scrolls: Treasures from the Caves of Qumran The University of Groningen researches one of the most important archeological findings ever: the Dead Sea Scrolls. The story of their discovery reads like a Dan Brown thriller, but the scrolls are even more exciting because they are real. Last century, the more than two-thousand-years-old manuscripts were discovered in caves close to Qumran, near the Dead Sea. With this discovery, we got the chance to study the origins and evolution of one of the roots of western society, the Bible. Whether one is religious or not, this matters as it is world heritage. Mladen Popović, director of the Qumran Institute of the University of Groningen, is a leading expert on the ancient scrolls. He wants to offer young, talented scientists in this field the chance to join him in his research. You can help. The Dead Sea Scrolls are like a time machine that shows us what people read, thought and felt centuries ago. They date back to the third century BC to the first century AD. The manuscripts were discovered between 1947 and 1956 in 11 caves close to the ancient site of Qumran, near the Dead Sea. They - almost a thousand of them! - are amongst the oldest known religious texts concerning Judaism, Christianity and the Bible.  Since its establishment in 1961, the Groningen Qumran Institute has been researching the Dead Sea Scrolls. The institute is unique in the Netherlands. It is the only center where all research evolves around ancient Judaism and the Dead Sea Scrolls. Internationally, the institute plays a leading role.  In 2013 Prof. Popović accomplished something no one else had done before. He succeeded in bringing a dozen original Dead Sea Scrolls - that are preserved by the Israel Antiquities Authority - to the Netherlands for an unique exhibition in the Drents Museum. Popović acted as curator and the exhibition attracted 140.000 visitors. The young director also received a prestigious European grant to research the writers of the manuscripts. Who wrote and copied the Dead Sea Scrolls? An interdisciplinary project, together with artificial intelligence, where 'the humanities meet science'.  Support usA lot of questions remain unresolved. The aim of the Qumran Institute is to create extra research positions to find answers. Popović’ wish is that young, talented scientists in his field get the opportunity to come to Groningen and research a specific subtopic of their interest - for one or two years. You can help him support a new generation of experts by donating via this website. Your help is needed since there is little research funding available in this niche.  You can also help us by sharing this page. Share it on Facebook, or tell your family, friends and colleagues about this initiative. Motivate others to support this research as well. Every donation helps us to move forward and unravel the secrets of the Dead Sea Scrolls.  Alumni in the Netherlands have already pledged 47.750 euro's. That means that we still need 24.250 euro's  to fund one postdoc researcher for one year. The Ubbo Emmius Fund will use every muscle to get the final funding for the first year, and we hope for your support.  € 46.471 Raised € 70.000 Target 66% Reached
Normal da4f890045d131ce7389c9d47468bac381db3e7c New knowledge on natural and cultural landscape dynamics Research on medieval trade routes, sod farming and a hill fort in Twente. Whether it comes to housing, new infrastructure, water storage, nature or agriculture, the Netherlands is continuously moving, and has always done so. Landscape Ecologist Harm Smeenge is developing a new discipline called ‘historical archaeology’ that combines several existing disciplines and research techniques. He chose the Northeast Twente region for his pilot study since "it is likely that there is no other place in the history of landscapes that shows more variety than Northeast Twente.” You can support Harm in his research.Harm Smeenge is a landscape ecologist and researcher at the Knowledge Centre Landscape (Dutch only) of the University of Groningen. The research of this Centre, led by Professor Theo Spek, focuses on the structure and history of the landscape and the Centre translates these insights into contemporary issues in the field of sustainability, cultural identity, spatial development and biodiversity. Harm conducts his research in Northeast Twente on the interaction between man and landscape over the past 10,000 years. He constructs this 'historical story' of Northeast Twente by linking together different disciplines: physical geography, (paleo) ecology and historical geography. Reconstructing landscapes based on this many different scientific disciplines and over such a long time span, has never been done before. Support this researchIn 2017 Harm Smeenge hopes to obtain his doctorate degree on the ecological history of Northeast Twente. The research techniques, that are used to date this landscape history precisely, are costly. The Knowledge Centre Landscape does not have sufficient resources for this unique research. Therefore Ubbo Emmius Fund seeks your support. In total, Harm Smeenge is in need of € 50,000 - for research that dates medieval trade routes, plaggen soils (sod farming) and the cultural and natural development of the medieval hill fort ‘Hunenborg’ between the building time until the present. The goal for the first part of the crowdfunding campaign is € 20, 000,-. This is intended for the date research of medieval trade routes and sod farming.  With your support Harm can do this date research.Would you please help him? Donate now and support Harm's research!    Dating of disappeared  landscapes   Medieval trade routesThe ‘Puntbeek’ is a fossil  Ice age remain of the Dinkel river system. This boundary brook was once a meter wide trickle and a trade route crossed the ‘Puntbeek’ during the Middle Ages. Back then, this road was paved on a sand bar in the wet peatlands. The road was important for trade between Oldenzaal and Hanover. Nowadays, the steep bank along the ‘Puntbeek’ shows waves of sand with black peat layers. These waves were caused by horse and wagons that transported tons of Bentheim sandstone. The sandstone was used for buildings, as well as fonts and troughs, that you can still find everywhere in eastern and northern parts of the Netherlands. The intensive transport, in combination with overgrazing, led to sand shifting and eventually caused the ‘Puntbeek’ to silt. Because of that, the road to Germany became too wet and lost its function. This can be traced back to the lack of ruts in more recent strata. Much later, because of sod farming, an “es” (an “upland field”) even arose on this spot. Reclamations in the past two centuries accelerated the drainage, and thus the ‘Puntbeek’ sank two meters by its own sediment. These are the visible patterns in the bank wall (see picture). These processes need further investigation over time. Plaggen soilsThe landscape history of Twente is unique, as it is the centre of the international plaggen soils. To gain more insight into the age and use of the “upland fields”, soil research is combined with pollen and soil chemistry research. Severe shortages of minerals were once the reason to fertilize with sods. The start of sod collection in the common fields has had a major impact on the landscape. Both the development of plaggen soils as the erosion and sedimentation that followed need further investigation (e.g. with a combination of pollen and dating research). About Harm SmeengeHarm Smeenge (1979) graduated in 2005 Wageningen University after he had acquired a very broad knowledge base through three courses in the field of forest and plant ecology, nature conservation and historical ecology. In addition to his PhD at the Knowledge Centre Landscape of the University of Groningen, Harm works in Ede at the Union of Forest Landscape advisor Landscape Ecology/ Historical ecology for owners of forest and nature. Photo Puntbeek: Elmer Spaargaren. € 16.925 Raised € 20.000 Target 84% Reached
Normal 401a37c9605ee6348c94699241593cd20a70084a Junior Scientific Masterclass 2016 Junior Scientific Masterclass was set up to give Medicine and Dentistry students the possibility to carry out scientific research alongside their studies. The students get this opportunity offered by means of an additional study grant. The financing of this grant is done in cooperation with the Ubbo Emmius Fund (UEF), the charity fund of the University of Groningen, by organizing a phonaton campaign, crowdfunding and additional fundraising. Since the cooperation with the UEF we raised a total amount of € 139.900 and awarded 23 students an additional grant!Junior Scientific Masterclass (JSM) was set up in 1999 for the purpose of providing medical students, who are interested in scientific research, extra opportunitities in addition to the regular degree progamme.The JSM programme has grown to be a professional - adapted for medical students- educational programme alongside Medicine and Dentistry. By offering extra courses and research positions it is possible to achieve a Honours-degree within their Bachelor programme and/or achieve a MD/PhD position combined with their residency programme. JSM aims to be within the UMC Groningen a hothouse  for future physician-scientists, who are willing to combine patient care and scientific research in the future.  There are research problems in practically every field: whether it has to do with improving a method of surgery, finding a safe sleeping pill, finding a better treatment for cancer, discovering a malaria vaccine or a miracle cure for obesity, everywhere doctors and medical specialists are needed who have expertise in these areas and who – in conjunction for instance with laboratory-based biologists or biochemists, or epidemiologists and statisticians working in clinical epidemiology – can ensure that research findings are applied in clinical situations. What is required is students (future doctors) who enjoy research, are fascinated by research questions and would perhaps like to continue doing research after they have qualified. With your donation to JSM Medicine and Dentistry students can do scientific research and further develop themseves by doing this programme. This will give students that extra financial leeway to make the most of their research and perhaps in the future to resolve the above issues. Last year, the alumni desk of the UEF also called with the alumni of the University of Groningen for JSM. As many as 573 alumni were willing to contribute. In total we raised € 27,900. JSM has supplemented this amount to € 30,000, so that three grants of € 10,000 were awarded. The students who received a grant are: Maroesjka Spiekman for her research "Can scars be healed with own fat?". Maroesjka researches whether an injection of own fat could reduce or cure severe scarring with patients. It is known that with lipofilling, where subcutaneous fat is removed in one place in the body and injected in another place, scars often fully or partially disappear. But it is still unknown how this exactly works. More knowledge could lead to better treatment of severe scarring. Stefan Knapen for his research "Prolonged sleep, wake and mood measurement with bipolar mood disorder". Stefan is studying aspects of the biological clock and the effects on mood disorders. There are many indications that there is coherence between the sleep, wake patterns and illness episodes for patients with bipolar disorder. When that connection is found mania or depression may possibly be recognized at an earlier stage. Willem Balder for his research "RNA-seq as molecular diagnostic resort?". Willem conducts research to genetic causes of high cholesterol levels. In this interview, he talks about his research and the importance of UEF-JSM Talent Grant.                                                  FLTR Stefan Knapen, Gerard Visser (UEF), Maroesjka Spiekman, Josca Westerhof (UEF) en Willem Balder. This year we would also like to give students this chance. We hope that you will be willing to support us! The Ubbo Emmius Fund, the fundraising institute of the University of Groningen, is an independent public benefit organization, which means that your donation is tax-deductible. In addition, your donation goes for 100% to the JSM. € 24.567 Raised € 20.000 Target 122% Reached